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Diagnosis of mitochondrial pathology


In our practice, an exact medical history is also collected from the family with the help of an extensive questionnaire. The physical examination, including the spine, is followed by the laboratory analysis. There is a urine test for citrulline (marker for NO), methylmalonic acid (provides information about meeting vitamin B12 requirements), nitrophenylacetic acid (worst enemy of mitochondrial function) and a blood test for mitochondrial activity. For this purpose, some vitamins and trace elements based on the diagnostics of Dr. Kuklinski determined via a blood sample. Optionally, the following can be determined: the formation of mitochondrial O2 radicals and the protein S100 with or without a stress test. The S100 protein revealed a defective blood-brain barrier, as occurs after cervical spine or craniocerebral trauma.

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